We are seeking a computational biologist interested in the genomic regulatory code for a joint position in the Laboratory of Computational Biology (Lab of Dr. Stein Aerts) and the Laboratory of Molecular Pathogenesis of Leukemia (Lab of Dr. Jan Cools) at the VIB and the Center for Human Genetics, University of Leuven, Belgium. Your research will focus on (1) developing algorithms for the prediction of transcriptional targets, cis-regulatory elements, and gene regulatory networks; and (2) integrate these methods with genome variation data (e.g., full genome sequences, whole exomes) and with gene expression data (microarrays, RNA-Seq) to predict genomic regulatory perturbations underlying oncogenesis. You have the opportunity to apply your methods both on patient samples and on animal model systems. Depending on your interests and background, you can combine bioinformatics with wet-lab experiments, for which a lab technician will assist you. You will be part of the Leuven SymBioSys Center of Excellence for Computational Systems Biology, where you will be surrounded by several other postdocs and students in a stimulating environment consisting of four bioinformatics research groups and four genomics labs.
Profile:
- We are seeking a motivated and enthusiastic computational biologist, preferably with a proven track record in gene regulatory bioinformatics (e.g., prediction of enhancers, promoters, transcription factor binding sites, gene regulatory networks).
- Experience with transcriptomics, cis-regulatory evolution, or the analysis of next-generation sequence data is a plus.
- PhD in Bioinformatics; PhD in engineering or computer science provided substantial insight in genetics; PhD in biological sciences provided substantial programming experience.
- Skills: genome informatics, statistics, programming.
Links:
- Laboratory of Computational Biology: http://med.kuleuven.be/bioinformatics/
- Laboratory of Molecular Pathogenesis of Leukemia: http://www.vib.be/Research/EN/Research+Departments/Department+of+Molecular+and+Developmental+Genetics/Jan+Cools/
- SymBioSys: http://homes.esat.kuleuven.be/~bioiuser/symbiosys2/
- Center for Human Genetics: http://med.kuleuven.be/cme/ and http://organigram.kuleuven.be/ext/5/50000622e.htm
- University of Leuven: http://www.kuleuven.be/english/
Highly motivated candidates can apply by sending a motivation letter, names and contact information for three references, publication list, and CV to stein.aerts@med.kuleuven.be.
Starting date: as soon as practically feasible.
Funding: available.
