地点: 德国 发布时间:2013-09-23 06:00:02 |
The Max Planck Institute for Immunobiology in Freiburg, Germany, offers
4 Postdoctoral Positions for Epigenetic Focus
All positions are available in the Department of Epigenetics (Head: Thomas Jenuwein) and are for an initial two-years appointment with the possibility of extension The Jenuwein group will relocate from the IMP in Vienna to the MPI in Freiburg (see photograph) during October 2008 and constitute a major component to establish a strong focus for epigenetic research. The epigenetic hub at the MPI Freiburg will comprise two full Max-Planck departments that combine two senior groups and 5 junior groups. In addition, there will be institutional infrastructure and service units to support mass-spectrometry/biochemistry, bioinformatics, Solexa-sequencing for genome-wide analyses, live cell imaging and FACS sorting. The MPI of Immunobiology is an international research institute (http://www.immunbio.mpg.de) and the working languages are German and English. Freiburg is ideally situated in the upper Rhine region with easy access to the Black Forest, Southern Germany, Switzerland and France.
The Jenuwein group represents a research profile to uncover the biological functions of histone lysine methylation in mammalian chromatin. Approaches used include the biochemical definition of histone lysine methyltransferases and demethylases, mass-spectrometry of histone modifications and genome-wide chromatin profiling (including deep-sequencing), the functional dissection of non-coding RNAs, the generation of mouse mutants, the analysis of chromatin signaling pathways (e.g. stress response) and overall chromosome structure (see webpage http://www.imp.ac.at/research/thomas-jenuwein).
For the following projects, the department is seeking highly motivated and experienced postdoctoral colleagues who will work in a team with PhD students and research assistants to analyse (1) histone modifications in pericentric heterochromatin, to define (2) RNA components of chromatin complexes, to discover (3) non-coding and double-stranded RNA transcripts in heterochromatic regions and to (4) extend ongoing screens for the identification of novel Su(var) genes in both Drosophila (collaboration with Prof. G. Reuter, Halle/S.) and mouse.
Candidates interested in these positions should have first-hand experience in either biochemistry/mass-spectrometry and the isolation of chromatin-modifying enzymes (projects 1-2), or in the chemistry and biogenesis of non-coding RNAs and RNA metabolism (projects 2-3), or in Drosophila genetics and gene mapping (collaborative project 4). Candidates must also have first-author publications in high-ranking journals and be able to successfully apply for independent fellowships within the next two years.
Salaries will be according to postdoctoral fellowships of the Max-Planck Society. A childcare facility is directly attached to the MPI of Immunobiology. Women are especially encouraged to apply; handicapped applicants with equal qualifications will be given preferential treatment.
Candidates should send their application comprising C.V., publication list, a 1-page research proposal and names of three referees to the Max-Planck-Institute of Immunology, Personnel Department, Stübeweg 51, 79108 Freiburg or directly via e-mail weigold@immunbio.mpg.de.
Informal inquiries can be directed to Thomas Jenuwein (Tel: +43-1-797-30-3200; e-mail: jenuwein@imp.ac.at; website: http://www.imp.ac.at/research/thomas-jenuwein).
Applications will be accepted until June 30th, 2008.
|
|
|
|
|
|
|
|
|
