地点:英国 发布时间:2013-09-17 03:23:21
英国布里斯托尔大学理论神经科学系招聘博士后
 
 
You will be a Postdoctoral Research Assistant with experience in whole-cell patch recording techniques to work on this project. Our recent work using this technique in-vivo on a simple model system, the young Xenopus tadpole, has led to remarkable progress in understanding spinal circuits. The features, connections and activity patterns of the major neuron groups controlling swimming and struggling locomotion have been defined. This knowledge offers a unique opportunity, in a vertebrate, to investigate the anatomical and functional development of defined neuronal networks where the details of both input and output signals are known. You will use whole-cell patch recording to investigate the roles of anatomically identified neurons in the initiation of motor responses. The project will then ask whether simple developmental rules allow neuronal circuits in the early vertebrate nervous system to self-assemble and control motor behaviour.
 
This project, in the Xenopus Neurobiology Research Group of Prof Alan Roberts and Dr Steve Soffe at the University of Bristol (http://www.bio.bris.ac.uk/research/neuro/xgroup.htm), is BBSRC funded. You will have experience in single neuron recording and very fine dissection methods and will work with two other postdocs: a neuroscientist in Bristol analysing neuron morphology and modelling anatomical development and network function; and a computational neuroscientist building anatomical and functional network models in the laboratory of Prof Roman Borisyuk, Department of Theoretical Neuroscience at the University of Plymouth. This position is available for up to three years from May 2009 or as soon as possible thereafter.
 
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