Postdoctoral Research Scientist
Weatherall Institute of Molecular Medicine
University of Oxford
University Grade 7: £28,839 – £35,469 p.a.
Regulation of pH and mitochondrial metabolism by hypoxia inducible factor 1
A 3-year Cancer Research UK funded Postdoctoral Research Scientist position is available to join the research group of Professor Adrian L. Harris, working on the molecular and cellular biology of tumour hypoxia. Applicants should possess a PhD or equivalent degree and have considerable experience in molecular biology and cell biology. They should have the ability to work in a team.
The project involves investigation of the role of hypoxia inducible carbonic anhydrases in survival, growth and metastasis of cancer: and interactions with treatment modalities that induce hypoxia. Mitochondrial metabolic pathways have critical effects on cancer cell survival in hypoxia and generate acid precursors, whose interactions with pH regulation will be investigated. A range of techniques including enzyme assays, cell cuture, inducible gene regulation by siRNA and bioinformatics will be required.
Informal enquiries can be made to Professor Adrian Harris by e-mail aharris.lab@imm.ox.ac.uk
To apply for this position please send a CV and covering letter giving details of three referees one of whom must be the current of most recent employer to Carol Eaton, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Headington, Oxford OX3 9DS,or email carol.eaton@imm.ox.ac.uk. Please quote reference number H809006 on all applications.
The closing date for applications is 5pm on Friday 27 March 2009. Applications after this date will not be accepted. Interviews will be held on Wednesday 15 April 2009.
The University is an Equal Opportunities Employer
