*Quantitative experimental exploration of proximal TCR signaling *
Dr. Rajat Varma and Dr. Martin Meier-Schellersheim
A postdoctoral position is available at the NIAID, NIH as part of a collaboration between the unit of T Cell Biophysics (http://www.niaid.nih.gov/labsandresources/labs/aboutlabs/lcmi/tcellbiophysicsunit/Pages/Varma.aspx)
and the Program in Systems Immunology and Infectious Disease Modeling (PSIIM)
(http://www.niaid.nih.gov/labsandresources/labs/aboutlabs/psiim/Pages/default.aspx).
We are looking for candidates interested in designing and performing quantitative experiments to improve our understanding of proximal T Cell Receptor signaling processes. A variety of optical and spectroscopic techniques such as Total Internal Reflection Fluorescence Microscopy, Spinning Disc Confocal Imaging, FRET Microscopy and Fluorescence Correlation Spectroscopy on live primary T cells will be used in these experiments. This work will be part of a crosstalk between computational modeling and quantitative experimental immunology.
Applicants should have (or be about to obtain) a degree in Biology, Chemistry, Physics or Engineering. Experience with modern microscopy techniques would be a plus but general experimental skills and a quantitative outlook are more important.
