地点: 其他国家 发布时间:2013-09-23 20:10:33 |
Several positions (Molecular/cellular Neurobiology & Protein Biochemistry/structural biology) are available immediately in the Laboratory of Molecular Neurobiology and Neuroproteomics at the Swiss Federal Institute of Technology in Lausanne (EPFL), Switzerland. Research efforts in the Lashuel’s laboratory cover the following topics: (1) Elucidating the structural basis of amyloid-associated toxicity in neurodegenerative diseases, including Alzheimer’s, Parkinson’s, and Huntington’s disease; (2) Understanding the role of quaternary structure in protein function and disease with emphasis on proteins involved in neurodegenerative and inflammatory diseases; (3) developing novel chemical and physical approaches and tools to monitor and control protein misfolding and protein aggregation in vitro and in vivo; (4) developing cellular models of neurodegeneration in Parkinson’s disease; (5) developing novel therapeutic strategies based on modulating protein aggregation and clearance. (6) Exploiting amyloid fibril formation for constructing polypeptide materials with potential applications in biotechnology and medicine.
We are looking for highly motivated individuals to work as members of an interdisciplinary group working at the interface of chemistry and biology. The candidate must have a strong skills and record of accomplishment in these areas. Good writing and communication skills are important, and the ability to be a team player and interact with several groups is a must. The candidate will benefit from working with a very dynamic and multidisciplinary group working at the interface of chemistry and biology. In addition, the EPFL offers attractive salaries and learning and working environments
Molecular and/or Cellular Biologists (1):
The applicant must have a Ph.D. degree in molecular and/or cellular biology (cloning, mutagenesis))and demonstrated experience in a broad range of molecular biology and cell culture techniques and extensive hands-on experience with confocal and fluorescence microscopy Additional experience in gene expression/knockdowns and protein trafficking and internalization pathways is a plus.
Interested applicant should submit a letter of interest, curriculum vitae and the names and addresses of three references to: Prof. Hilal A. Lashuel at the address shown above or by email: hilal.lashuel@epfl.ch)
|
|
|
|
|
|
|
|
|
