地点: 美国 发布时间:2013-09-17 02:32:09 |
The primary focus of the laboratory is to explore how certain tumor suppressor pathways influence developmental processes. Two current projects explore (1) how the Arf tumor suppressor gene is regulated and controls aspects of development, including vascular remodeling in the developing eye; and (2) how the regulation of Rb protein function by Cyclin dependent kinases influences skeletal muscle differentiation and the biology of skeletal muscle-derived cancers. Experimental approaches take advantage of existing mouse models and cell culture-based systems and may include the development of new mouse models to address specific experimental questions. Standard molecular and cellular biology and histology techniques are routinely used.
Candidates with MD or PhD are eligible. Send applications to Dr. Stephen X. Skapek, Biological Sciences Division of the University of Chicago (sskapek@peds.bsd.uchicago.edu).
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