地点: 美国 发布时间:2013-09-17 03:28:20 |
A post-doctoral position is available beginning summer of 2009 (start date flexible) for a recent PhD interested in studying effects of the extracellular matrix, integrin signaling, and tissue stiffness on cell cycle progression and differentiation.
Much of our work is directed at understanding the mechanisms by which matrix remodeling and changes in tissue stiffness regulates integrin signaling and the cell cycle in vascular smooth muscle cells (VSMCs). Mechanism-based studies in vitro use primary VSMCs and hydrogel-based cell culture to recapitublate the substratum elasticity that VSMCs encounter in vivo. Complementary studies in genetically engineered mice examine changes in tissue stiffness, signaling and cell cycle progression that occur after vascular injury and during atherogenesis in vivo.
We always encourage lab members and applicants to suggest potential new projects falling within our research interests, broadly defined. See http://www.med.upenn.edu/camb/faculty/cbp/assoian.html OR http://www.med.upenn.edu/pharm/faculty/assoian/assoian.html for further descriptions of our research.
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