地点: 美国 发布时间:2013-09-17 01:32:18 |
NIH funded postdoctoral position is immediately available for highly motivated individuals seeking to build a career in cancer biology. The lab is interested in basic, mechanistic and translational research focusing on bzip transcription factor, Nrf2 that regulates several electrophile detoxification and cytoprotective genes and promotes tumorigenesis. Previous work from our lab has shown that gain of Nrf2 function in lung tumor cells, due to mutation in its inhibitor, Keap1, promotes tumor growth and confers therapeutic resistance. Primary focus of this project is to understand the novel pathways regulated by Nrf2 in cancer cells which drive lung tumorigenesis. Another focus of the project is to study the role of Nrf2 in modulating glucose flux and metabolism in cancer cells. Experience with mice xenograft models is desired. Candidates with PhD in Cancer Biology, Biochemistry and molecular biology can contact by email. Send CV with names of 3 references to Shyam Biswal, School of Public Health, Johns Hopkins University, by email Biswallab@gmail.com
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