Postdoctoral Research Associate/Instructor Position to study nuclear hormone receptor-mediated gene regulation in pathophysiology and diseases. Nuclear hormone receptors are ligand-dependent transcription factors. We use transgenic, knockout and humanized mice, disease models, and molecular biology to study gene regulation controlled by nuclear receptors such as PXR (Nature 406:435-39, 2000; Molecular Endocrinology 22:868-80, 2008; Molecular Pharmacology 76:604-11, 2009), CAR (JBC 284:25984-92, 2009), LXR (Hepatology 47:1331-42, 2008; Gastroenterology 134:556-67, 2008; Endocrinology 149:3778-88, 2008; JBC 284:30113-21, 2009), ROR (Molecular Pharmacology 73:891-9, 2008), and GR (Cancer Research 68:7386-93, 2008). We are most interested in the implications of these gene regulatory events in metabolic diseases such as obesity and diabetes, cancer, liver diseases, oxidative stress, and endocrinology. (http://www.pharmacy.pitt.edu/directory/dir_grad.lasso?Last=XieW). Send CV and names of three references to Wen Xie, MD, PhD, Associate Professor and Associate Director, Center for Pharmacogenetics, University of Pittsburgh, Pittsburgh, PA 15261. Email firstname.lastname@example.org.